Even Freeza with his strength wouldn’t be able to puncture a hole in the barrier. Even if he were able to, he would pass out from the effects of trying to pass through the barrier. And even if he were able to get out, the creatures that linger outside of it would make a meal out of him.

Though he can’t breach it, just attempting to do so will get him the same effects. So he’ll essentially passout from trying. He’ll feel weakened for a few hours when he awakes, but the effects will disappear.